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Aeroplysinin-1 is a secondary metabolite that is contained in marine sponges and important for the chemical defense of these sessile invertebrates. It shows a wide antitumor activity and has antibiotic, antiangiogenic and antiviral effect as well.
Reported effectsCharcteristics
Product Data SheetChemical name 2-[(1S,6R)-3,5-Dibrom-1,6-dihydroxy-4-methoxycyclohexa-2,4-dien-1-yl]acetonitril Molecular formula C9H9Br2NO3 Molecular weight 338.98 g/mol CAS-number 28656-91-9 Aeroplysinin-1 100308 Aeroplysinin-1 COC1=C(C(C(C=C1Br)(CC#N)O)O)Br Solubility ethanol, methanol and DMSO Source Aplysina aerophoba Purity > 99% Appearance off-white powder Notices
Long term storage -20 °C (protected from moisture) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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Isofistularin-3 is a natural, marine alkaloid belonging to the group of bromotyrosine-derivatives. It is a cytotoxic isoxazoline compound and exhibits amongst others deterrent activity.
Charcteristics
Product Data SheetChemical name (5S,10R)-7,9-dibrom-N-[(2R)-3-[2,6-dibrom-4-[2-[[[(5S,10R)-7,9-dibrom-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]-deca-2,6,8-trien-3-yl]carbonyl]amino]-1-hydroxyethyl] phenoxy]-2-hydroxypropyl]-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-trien-3-carboxamid Molecular formula C31H30Br6N4O11 Molecular weight 1114.01 g/mol CAS-number 87099-50-1 Isofistularin-3 159041 Isofistularin-3 COC1=C([C@@H]([C@]2(CC(=NO2)C(=O)NCC(COC3=C(C=C(C=C3Br)C(CNC(=O)C4=NO[C@@]5(C4)C=C(C(=C([C@@H]5O)Br)OC)Br)O)Br)O)C=C1Br)O)Br Solubility ethanol, methanol and DMSO Source Aplysina aerophoba Purity > 99% Appearance white to off-white solid Notices
Long term storage -20 °C (protected from moisture and light) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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Acetyl verongiaquinol is a semi synthetic derivative of the secondary metabolite Verongiaquinol from the marine sponge Aplysina aerophoba.
Charcteristics
Product Data SheetChemical name 4-acetoxy-2,6-dibromo-4-carbamoylmethylcyclohexa-2,5-dien-1-one Molecular formula C10H9Br2NO4 Molecular weight 366.99 g/mol CAS-number 153535-66-1 Acetyl verongiaquinol - Acetyl verongiaquinol CC(=O)OC1(CC(N)=O)C=C(Br)C(=O)C(=C1)Br Solubility chloroform, DMSO Source Aplysina aerophoba, semi synthetic Purity > 99% (HPLC) Appearance solid Notices
Long term storage -20 °C (protected from moisture) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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Avarol is a secondary metabolite from the marine sponge D. avara. It is a sesquiterpenoid hydroquinone.
Charcteristics
Product Data SheetChemical name 2-[[(1R,2S,4aS,8aS)-1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl]methyl]-1,4-Benzendiol Molecular formula C21H30O2 Molecular weight 314.46 g/mol CAS-number 55303-98-5 PubChem CID 72185 SMILES CC1CCC2(C)C(CCC=C2C)C1(C)CC3=C(O)C=CC(=C3)O Solubility ethanol, methanol and DMSO Source Dysidea avara Purity > 99% (HPLC) Appearance brown solid Notices
Long term storage -20 °C (protected from moisture) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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Aerothionin is an alkaloid with two isoxazoline moieties and belongs to the bromotyrosine derivatives. It is a secondary metabolite that, amongst others, occurs in Aplysina cavernicola in larger amounts.
Charcteristics
Product Data SheetChemical name (5S,5'S,10R,10'R)-N,N'-1,4-butandiylbis[7,9-dibrom-10-hydroxy-8-methoxy-1-Oxa-2-azaspiro[4.5]deca-2,6,8-trien-3-carboxamide Molecular formula C24H26Br4N4O8 Molecular weight 818.10 g/mol CAS-number 28714-26-3 Aerothionin 301120 Aerothionin COC1=C(Br)C(O)C2(CC(=NO2)C(=O)NCCCCNC(=O) C3=NOC4(C3)C=C(Br)C(=C(Br)C4O)OC)C=C1Br Solubility ethanol, methanol and DMSO Source Aplysina cavernicola Purity > 99% (HPLC) Appearance solid Notices
Long term storage -20 °C (protected from moisture) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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Homoaerothionin is a symmetric isoxazoline alkaloid and differs from Aerothionin in the length of the bridging alkyl chain. The secondary metabolite belongs to the bromotyrosine derivatives.
Charcteristics
Product Data SheetChemical name (5S,5'S,10R,10'R)-N,N'-1,5-Pentandiylbis[7,9-dibrom-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-trien-3-carboxamide Molecular formula C25H28Br4N4O8 Molecular weight 832.13 g/mol CAS-number 34232-66-1 Homoaerothionin 100315 Homoaerothionin COC1=C(Br)C(O)C2(CC(=NO2)C(=O)NCCCCCNC(=O) C3=NOC4(C3)C=C(Br)C(=C(Br)C4O)OC)C=C1Br Solubility ethanol, methanol and DMSO Source Aplysina cavernicola Purity > 99% (HPLC) Appearance solid Notices
Long term storage -20 °C (protected from moisture) Handling Prepared solutions need to be stored in tightly sealed vials at -20 °C. THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
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α-Chitin is a biopolymer made of β-1,4 glycosidic linked acetylglucosamine monomers and the second most abundant polysaccharide. Essentially, it serves for structure formation. This is also its role in the composition of the complex scaffolds of marine sponges.
Charcteristics
Product Data SheetChemical name (IUPAC) (1→4)-2-acetamido-2-deoxy-β-D-glucan Form biopolymer Alpha-Chitin, 3D-sponge scaffold N-Acetylglucosamine Molecular formula of the monomer C8H13NO5 Molecular weight of the monomer 203.19 g/mol CAS number 1398-61-4 Alpha-Chitin, 3D-sponge scaffold 6857375 Solubility insoluble Melting point > 300 °C (Zersetzung) Degree of acetylation > 90 % Source Aplysina aerophoba Notices
Storage store dry Handling no special notes THIS PRODUCT IS SUITABLE FOR RESEARCH ONLY AND NOT SCHEDULED FOR DIAGNOSTIC OR THERAPEUTIC INDICATIONS. NOT TO BE USED ON HUMANS.
